Topic
Topic
Multiple Sclerosis
Sometimes the severity of progressive multiple sclerosis improves naturally, and we know little about this.
Setup
Design
R
Realized in R-Statistics, SQL
We examined if the symptoms of progressive multiple sclerosis can improve reliably and clinically meaningfully even if not treated.
After selecting patients with progressive multiple sclerosis who received no treatment and had no relapses in two years, we classified patients as experiencing disease improvements. Disease improvements were defined based on the expanded disability scale by a clinically meaningful improvement from baseline which needed to be lasting for 6 months or longer, measuring confirmed disability improvements. The results showed that indeed there was a minority (< 5%) of untreated progressive multiple sclerosis patients with spontaneous meaningful and lasting disease improvements.
You can read the abstract and view the poster after the ACTRIMS 24 homepage was updated.